Research Programs

The mission of the Cancer Biology and Genetics (CBG) Program is to pursue research bridging basic and clinical aspects of the genesis, progression, prognosis, prevention, and treatment of cancer.

The research activities of the Cell Biology Program are directed towards understanding the molecular mechanisms that control normal cell behavior and how these are disrupted in cancer. The overall mission of this program is to identify, through the advancement of knowledge in cell biology, alterations that promote cancer progression and new opportunities for treating the disease.

The aim of computation biology is to build computer models that simulate biological processes from the molecular level up to the organism as a whole and to use these models to make useful predictions.

Investigators in the Developmental Biology Program study the mechanisms that control cell proliferation, cell differentiation, tissue patterning and tissue morphogenesis.

The scope of immunology at the Sloan-Kettering Institute incorporates a wide range of areas and expertise (both basic and clinical). A strength of the Immunology Program is the ability to translate laboratory findings into effective clinical applications.

Research in the Molecular Biology Program is directed at understanding how cell growth is regulated.

The Molecular Pharmacology and Therapeutics Program has as its goals the conception, design, and synthesis of new anticancer and antiviral agents, elucidation of mechanisms of action and resistance of anticancer agents, preclinical evaluation and toxicology of promising new agents, translational research bearing on radiation and chemotherapy, risk assessment, and broader aspects of cancer etiology, prevention, and pathogenesis.

The aims of the Structural Biology Program are to understand biological function at the structural and mechanistic levels, to determine the structural basis of disease-related alterations in biological macromolecules, and to aid the development of novel anti-tumor agents through collaborative studies.