The Urologic Oncologic Research Laboratory is devoted to translational studies of the biology of the four types of genitourinary cancer -- prostate, bladder, kidney, and testis. Specifically, our research focuses on cell-cycle and apoptotic regulatory systems; the identification and validation of novel tissue markers of progression; the design and testing of strategies for accurate and efficient sampling of cancer from the prostate; and the development of new models of progression and decision-analysis using medical informatics.
In collaboration with other institutions, such as Cornell University and Stanford University, our investigators are designing an optical imaging system and new contrast agent (a monoclonal antibody linked to a fluorophore) to image a small number of prostate cancer cells in vivo in real time.