Career Opportunities Available tenure track positions 
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The Molecular Pharmacology and Chemistry Program has as its goals the conception, design, and synthesis of new anticancer and antiviral agents; elucidation of mechanisms of action and resistance of anticancer agents; preclinical evaluation and toxicology of promising new agents; translational research bearing on radiation and chemotherapy; risk assessment; and broader aspects of cancer etiology, prevention, and pathogenesis.
This program functions as the conduit for bringing discoveries in the basic biological sciences, generated from cancer-related molecular pharmacology and from the other research programs, to preclinical and clinical evaluation. More than half of the members of this program are engaged in laboratory-associated clinical investigation.
As the largest program in Memorial Sloan-Kettering, Molecular Pharmacology and Chemistry includes faculty immersed in the whole spectrum of pharmacological fields, ranging from drug development, drug sensitivity and resistance, molecular biology of drug action, cell signaling, chemoprevention, transcriptional regulation, neuropharmacology, antibody and cytokine therapy, tumor antigens, to the development of improved tumor assays.
The near future should see several of the discoveries from the laboratory tested in the clinic. The vaccine program, utilizing synthetic carbohydrate antigens, is being expanded and evaluated in breast, ovarian, and prostate tumors. Deoxyepithilone B will be evaluated further in preclinical models, and a pharmaceutical partner is sought for its clinical development; gene therapy protocols using drug resistance genes will be written for patients with lymphoma and breast cancer; and new treatment strategies for patients, depending on tumor phenotyping and genotyping, are in development.
